AI-Designed Drug Enters First Human Clinical Trials for OCD
A groundbreaking drug developed entirely by artificial intelligence is set to enter human clinical trials for the first time. This innovative medication, aimed at treating obsessive-compulsive disorder (OCD), was discovered using AI systems from the Oxford-based biotech firm Exscientia. Typically, drug development takes around four and a half years to reach this stage, but Exscientia claims it has achieved this milestone in less than 12 months thanks to AI technology.
The drug, named DSP-1181, was formulated by deploying algorithms to analyze potential compounds against a vast database that includes genetic factors specific to patients. In an interview with the BBC, Exscientia's CEO, Professor Andrew Hopkins, emphasized that the trials represent a "key milestone in drug discovery." He explained that finding the right drug molecules involves "billions" of decisions, making the creation process complex. However, with AI, "the beauty of the algorithm is that it is agnostic and can be applied to any disease."
The integration of AI in drug development follows its successful application in diagnosing illnesses and analyzing patient data, marking a natural evolution in its role within medicine. Nonetheless, the emergence of AI-created drugs raises important questions: Will patients embrace medications designed by machines? How will these drugs differ from those crafted by human researchers? Who will establish the guidelines for AI's role in drug discovery?
As the clinical trials kick off in March, Hopkins and his team aim to address these critical questions, paving the way for the future of AI in medicinal development.